There diversity in sterols in the membrane which could

There
are many different types of disorders that can occur from specific lipids. If there
is a high concentration of saturated fatty acids in the membrane, there can be
an increased risk of metabolic syndrome of heart disease.7 Too much
LDL or too little HDL, therefore can increase the risk of stroke, heart attack,
hypertension or atherosclerosis. This is because the increase in cholesterol
causes the membrane to increase triglyceride storage and the membrane will
become more compact. Increased levels of HDL can also decrease the effects of
increased LDL levels.8 Also, excess non-cholesterol sterols are
taken up by the gut in order to prevent accumulation in other areas.7
High levels of triglycerides could also cause increase the chances of getting
pancreatitis. This is thought to be because the increase of chylomicrons in the
blood can cause obstruction to capillaries leading to ischemia and increased
Hydrogen concentration in the blood. This will cause damage and expose
triglycerides to pancreatic lipases. As these triglycerides are being degraded
can lead to cytotoxic damage which stimulates an inflammatory response.9
Typically, unsaturated fatty acids are essential in the membranes in the brain.
These are considered healthy fats and come from omega three fatty acids found
in vegetable oils and other foods.10 Deficiency of these unsaturated
fatty acids will cause mental dysfunction.7

            It is also important to note that
normally functioning membranes are found to have low levels of ergosterol. The
function of ergosterol is to organize lipid packing at low concentrations and
allow for a wider range of dietary sterols to be incorporated into the
membrane. If there are high levels of erogsterol there will be less diversity
in sterols in the membrane which could alter ion transport across the membrane
or membrane fluidity. Diversity of lipids in the membrane is essential to
normal tissue function. Also, if there are levels of ergosterol present that
are higher than the levels of stigmasterol there could be an impairment of
lipid packaging in the cell membrane causing membrane issues with cellular signaling
and membrane transport.7

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